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Can J Infect Dis Med Microbiol. Mar-Apr;26(2) Empyema caused by Clostridium bifermentans: A case report. Edagiz S(1), Lagace-Wiens P(2), Embil . Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of resistance of this organism to. We report a case of recurrent Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of .

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Clostridium bifermentans – Wikipedia

In Octobera year-old woman with history of abnormal uterine bleeding status post an uncomplicated endometrial ablation 5 months prior developed new onset dysuria and grayish, malodorous vaginal discharge. Fatal cloetridium spontaneous endometritis resulting from Clostridium sordellii. The abdomen was tender to palpation in the right upper quadrant.

A review of systems was otherwise negative. However, in more recent reports, this organism has been documented as a cause of septic arthritis, osteomyelitis, soft tissue infection, abdominal infections, brain abscess, bacteremia and endocarditis 79 — Because no cultures were positive in our case, assays to study toxin elaboration were not possible.

A septic embolus would also be possible as a mechanism of infection, although blood cultures were negative. Pleural empyema due to Clostridium difficile and Clostridium cadaveris.


Chest radiograph demonstrating a right-sided pneumothorax white arrow and right lower lobe consolidation black arrow.

Empyema fluid obtained at the time of surgery was submitted to the microbiology laboratory. On hospital day 4, her edema had improved and the team was able to examine her pupils, which were found to be fixed and dilated. His antimicrobial therapy was changed to a combination of piperacillin-tazobactam and levofloxacin, and heparin was initiated as treatment for the pulmonary embolus. Thus, the patient remained on broad-spectrum antimicrobials during his stay in hospital.

He denied the use of intravenous recreational drugs. The patient gradually improved over a period of several weeks. Please review our privacy policy. She developed profound anasarca, and a repeat pelvic or ophthalmologic exam was unable to be performed because of massive edema.

Empyema caused by Clostridium bifermentans: A case report.

Scand J Infect Dis. This article has been cited by other articles in PMC. Tobramycin, clindamycin, and doxycycline were added for sepsis. After the second surgery, the antimicrobial therapy was changed to a combination of ceftriaxone and metronidazole.

Am Rev Respir Dis. Infect Immun ; A large pleural effusion was demonstrated on chest radiography.

Clinical features bufermentans clostridial bacteremia: On physical examination at the time of presentation, the patient was noted to be febrile, with an oral temperature of Further characterization of this rare pathogen is warranted.


In both of the previously published cases of C bifermentans empyema as well as the current case, it is unclear whether infection occurred secondary to hematogenous spread, inhalation or aspiration of the organism, although inhalation was favoured in the report by Jonsson et al Our case represents a novel manifestation of C bifermentans in regards to both site and severity. Twenty-nine days after the initial surgical procedure 44 days postadmissionthe patient was taken back to the operating room for a second bifermntans, right rib resection and empyema drainage.

Thus, the genes accountable for the toxicity towards Anopheles are different than those controlled by the cry operon; rather, the toxins selectively target Aedes mosquito larvae, in which they cause high mortality. National Center for Biotechnology InformationU. An exceptional agent of endocarditis.

Clostridium bifermentans (Weinberg and Seguin) Bergey et al. ATCC &reg

More than species and subspecies have been recognized to date. Necrotising pneumonia and empyema caused by Clostridium bifermentans. Clostridium bifermentans and C. Received Dec 16; Accepted May 9.